NAC: N-Acetylcysteine-Cysteine

A sulphur-containing amino acid, antioxidant, which plays an important role for the liver, kidneys, skin and lungs.

N-Acetyl Cysteine is a derivative of a non-essential amino acid: cysteine.

This sulphur-containing amino acid is naturally synthesised by the body from other amino acids (methionine, serine…). It is also found in certain foods such as garlic, onion, broccoli, wheat germ, brewer’s yeast, eggs, fish, meat… NAC is more rapidly and completely absorbed than the cysteine from which it originates, so its bioavailability is better (90%). Immediately metabolised after intake, it is distributed to the liver, kidneys, lungs and bronchial mucus. It then participates in many metabolic functions:

• Synthesis of fatty acids
• Formation of skin, nails and hair
• Production of hormones

It also has an antioxidant role because it contains sulphur and is essential for the synthesis of Glutathione, the "master antioxidant" of the body. It is called this because it is the main water-soluble antioxidant of cells thanks to its electron-donating capacity allowing it to destroy free radicals and to recycle and restore the powers of vitamins C and E. Glutathione is part of the composition of the major antioxidant enzyme of the body (with superoxide dismutase and catalase): glutathione peroxidase, which eliminates hydrogen peroxide produced by cellular respiration. NAC is consumed at very high doses in cases of paracetamol poisoning (beware of excessive Doliprane) because glutathione detoxifies the liver. It is also used for its mucolytic action. It will therefore be used against respiratory conditions:

• Chronic bronchitis
• Smoking cessation
• Respiratory disorders related to thickening of mucus.

NAC offers the precious benefits of sulphur for the liver, kidneys, skin and lungs. However, it should be avoided when taken at the same time as penicillin-based antibiotics and is not recommended for pregnant women.